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Caspase 2 antibody [4i13(C2)]

Orthogonal
Anti-Caspase 2 antibody [4i13(C2)] used in Western Blot (WB). GTX18029

Cat. No. GTX18029

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 4i13(C2)

Isotype

 IgG1

Application

 WB, ELISA

Reactivity

 Human
Package
50 μl ($399)
See all Caspase 2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
ELISA Assay dependent
Not tested in other applications.

Calculated MW

51 kDa. ( Note )

Product Note

Recognizes endogenous levels of human procaspase-2 at ~48kD as well as its 14 and 12kD cleaved fragments.

PROPERTIES

Form

Liquid

Buffer

10mM Sodium HEPES pH7.5, 150mM Sodium Chloride, 0.1mg/ml BSA, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Synthetic peptide corresponding to the C-terminal portion of human caspase-2.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CASP2 , ICH1 , NEDD2 , PPP1R57 , caspase 2

Background

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

Database

Research Area

DATA IMAGES

Anti-Caspase 2 antibody [4i13(C2)] used in Western Blot (WB). GTX18029

GTX18029 WB Image

Orthogonal

WB analysis of untreated or etoposide-treated Jurkat cell lysate using GTX18029 Caspase 2 antibody [4i13(C2)].

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399